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Benedetto Grimaldi

Senior Researcher Tenured - Principal Investigator
Molecular Medicine
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About

Dr. Benedetto Grimaldi obtained in 2001 the degree in Biological Science with a summa cum laude from the University of Rome “La Sapienza”.

After obtained a PhD in Genetics and Molecular Biology under the supervision of Dr. Paola Ballario (University of Rome, La Sapienza, Italy), an expert in the study of epigenetics and signal transduction, Dr. Grimaldi transitioned into a postdoctoral fellowship under the mentorship of Prof. Sassone-Corsi (University of California, Irvine, USA), a leader in the field of circadian clock, metabolism and epigenetics.

In 2011 Dr. Grimaldi joined the Drug Discovery and Development (D3) department at the Istituto Italiano di Tecnologia (IIT), where he began pursuing his own line of research focused on the study of “clock-related pathologies”, and on the identification and evaluation of novel molecules with “clock modulator” activity for therapeutic applications.



All Publications
2022
Ugolini A., Mongiardini V., Vecchio D., Scarpelli R., Grimaldi B.
Bactericidal-Autophagy Inhibitors to Treat Recurring Uropathogenic Infections and Cancer (P033). IX EFMC-YMCS 2022, September 8-9, 2022 - Nice (France)
EFMC Young Medicinal Chemists' Symposium
Poster Conference
2022
Ugolini A., Mongiardini V., Vecchio D., Scarpelli R., Grimaldi B.
Bactericidal-Autophagy Inhibitors to Treat Recurring Uropathogenic Infections and Cancer (P209). XXVII EFMC-ISMC 2022, September 4-8, 2022 - Nice (France)
EFMC International Symposium on Medicinal Chemistry
Poster Conference
2021
Klionsky D.J., Abdel-Aziz A.K., Abdelfatah S., Abdellatif M., Abdoli A., Abel S., Abeliovich H., Abildgaard M.H., Abudu Y.P., Acevedo-Arozena A., Adamopoulos I.E., Adeli K., Adolph T.E., Adornetto A., Aflaki E., Agam G., Agarwal A., Aggarwal B.B., Agnello M., Agostinis P., Agrewala J.N., Agrotis A., Aguilar P.V., Ahmad S.T., Ahmed Z.M., Grimaldi B., et al.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy, vol. 17, (no. 1), pp. 1-382
2020
Blazevits O., Bolshette N., Vecchio D., Guijarro A., Croci O., Campaner S., Grimaldi B.
MYC-associated factor max is a regulator of the circadian clock
International Journal of Molecular Sciences, vol. 21, (no. 7)
2020
Di Cristo L., Grimaldi B., Catelani T., Vazquez E., Pompa P.P., Sabella S.
Repeated exposure to aerosolized graphene oxide mediates autophagy inhibition and inflammation in a three-dimensional human airway model
Materials Today Bio, vol. 6