Non-coding Genome - Francesco Nicassio

The Non-coding Genome Group studies the function and regulation of non-coding transcripts, focusing on the molecular mechanisms in control of gene expression regulation and how they shape the identity and properties of human stem cells during cancer evolution

WHAT? understanding the role played by ncRNAs in transcriptional/epigenetic plasticity

WHERE? physiology (development) and human (cancer) disease, focusing on cancer evolution (drug resistance, metastasis)

HOW? integration of Experimental models with Computational and –omics methodologies